XL413 xHCl
XL413 HCl is a potent and selective, ATP-competitive inhibitor of Cdc7 kinase (IC50: 3.4 nM), with additional activity against PIM1 and CK2. It has been utilized in research to study DNA replication and cell cycle progression in various cancer models, demonstrating utility in both in vitro and in vivo experimental settings.
Product Specifications
CAS Number
1169562-71-3
Product Name Alternative
BMS-863233 xHCl, BMS-863233 HCl, Cdc7, CK2, Casein Kinase, CaseinKinase, Pim1, XL413 hydrochloride, XL413 Hydrochloride, XL-413 Hydrochloride, XL 413 Hydrochloride
Field of Research
Cell Biology, Epigenetics & Chromatin, Metabolism Research, Signal Transduction, Stem Cell & Developmental Biology
Purity
99.37% (May vary between batches)
Solubility
DMSO:3.1 mg/mL; H2O:9 mg/mL
Smiles
Clc1ccc2oc3c (nc ([nH]c3=O) [C@@H]3CCCN3) c2c1. xCl
Molecular Formula
C14H12ClN3O2. xHCl
Molecular Weight
326.18
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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