Quizartinib HCl
Quizartinib (AC220) is a potent and selective oral inhibitor of class III receptor tyrosine kinases, primarily targeting FLT3. It is a key research tool for studying FLT3-ITD mutant acute myeloid leukemia (AML), demonstrating efficacy in both cellular assays and in vivo models to investigate proliferation and apoptosis mechanisms.
Product Specifications
CAS Number
1132827-21-4
Field of Research
Cardiovascular Research, Cell Biology, Pharmacology & Drug Discovery, Signal Transduction
Smiles
O (CCN1CCOCC1) C=2C=C3C (N4C (S3) =NC (=C4) C5=CC=C (NC (NC=6C=C (C (C) (C) C) ON6) =O) C=C5) =CC2.Cl.Cl
Molecular Formula
C29H34Cl2N6O4S
Molecular Weight
633.59
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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