Noberastine maleate
Noberastine maleate is a potent and selective peripheral histamine H1 receptor antagonist derived from nor-astemizole. It exhibits rapid oral absorption with peak plasma levels at 2 hours and maximal antihistaminic activity at 4 hours, showing dose-dependent inhibition of histamine-induced weal and flare reactions in preclinical studies without central nervous system effects.
Product Specifications
CAS Number
111922-05-5
Field of Research
Immunology & Inflammation, Neuroscience, Pharmacology & Drug Discovery
Smiles
OC (/C=C\C (O) =O) =O.CC1=CC=C (O1) CN2C3=NC=CC=C3N=C2NC4CCNCC4.OC (/C=C\C (O) =O) =O
Molecular Formula
C25H29N5O9
Molecular Weight
543.53
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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