Afegostat TFA
Afegostat (Isofagomine, AT2101) is a pharmacological chaperone and potent acid β-glucosidase (GCase) inhibitor (K (i) ~30 nM) investigated for Gaucher disease. In vivo studies, such as administration in mouse models (e.g., V394L), demonstrated increased GCase activity in visceral tissues and brain, supporting its research use in lysosomal storage disorders.
Product Specifications
CAS Number
1084896-50-3
Field of Research
Immunology & Inflammation, Metabolism Research
Smiles
C (C (O) =O) (F) (F) F.C (O) [C@@H]1[C@@H] (O) [C@H] (O) CNC1
Molecular Formula
C8H14F3NO5
Molecular Weight
261.2
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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