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NS-0011

NS-0011 is a small molecule inhibitor that blocks CDK5 nuclear translocation, leading to its nuclear accumulation. This mechanism suppresses cancer cell proliferation in vitro and inhibits tumor growth in vivo xenograft models, supporting its use in oncology research.

Product Specifications

CAS Number

1076234-33-7

Smiles

N (N1C (=O) C (C) =C (C) C1=O) C=2N=C (Cl) C (C (F) (F) F) =CC2

Molecular Formula

C12H9ClF3N3O2

Molecular Weight

319.67

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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