MRT-92 HCl salt
MRT-92 is a subnanomolar, selective Smoothened (Smo) receptor antagonist, inhibiting Hedgehog pathway activity in cellular assays and rodent cerebellar granule cell proliferation. This Smo inhibitor, targeting the 7TM domain cavity, is a valuable research tool for studying Hh-driven cancers and developmental processes in both in vitro and in vivo models.
Product Specifications
CAS Number
1428307-52-1
Smiles
Cl.COc1cc (cc (OC) c1OC) C (=O) NC (=N) Nc1ccc (C) c (NC (=O) c2ccc (CCc3ccccc3) cc2) c1
Molecular Formula
C33H35ClN4O5
Molecular Weight
603.12
Storage Conditions
-20°C
Notes
For research use only.
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