Lanabecestat HCl
Lanabecestat (AZD3293/LY3314814) is an orally bioavailable, brain-penetrant BACE1 inhibitor with slow off-rate kinetics. It has demonstrated dose- and time-dependent lowering of Aβ peptides in plasma, CSF, and brain in preclinical studies, supporting its investigation for Alzheimer's disease research in both in vitro and in vivo models.
Product Specifications
CAS Number
1383986-31-9
Field of Research
Neuroscience
Smiles
Cl.CO[C@H]1CC[C@@]2 (Cc3ccc (cc3[C@@]22N=C (C) C (N) =N2) -c2cncc (c2) C#CC) CC1
Molecular Formula
C26H29ClN4O
Molecular Weight
448.995
Storage Conditions
-20°C
Notes
For research use only.
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