BE-16627B
BE-16627B is a selective metalloproteinase inhibitor isolated from Streptomyces sp., effectively suppressing enzymes like stromelysin and 92 kDa gelatinase. It demonstrates dose-dependent inhibition of collagenolysis (IC50 = 25 μM) in synovial cell cultures without cytotoxicity, making it a valuable research tool for studying matrix remodeling in arthritis and cancer models.
Product Specifications
CAS Number
137530-61-1
Smiles
C (C (N[C@H] (C (N[C@@H] ([C@@H] (C) C) C (O) =O) =O) CO) =O) (CC (NO) =O) CC (C) C
Molecular Formula
C16H29N3O7
Molecular Weight
375.42
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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