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BE-16627B

BE-16627B is a selective metalloproteinase inhibitor isolated from Streptomyces sp., effectively suppressing enzymes like stromelysin and 92 kDa gelatinase. It demonstrates dose-dependent inhibition of collagenolysis (IC50 = 25 μM) in synovial cell cultures without cytotoxicity, making it a valuable research tool for studying matrix remodeling in arthritis and cancer models.

Product Specifications

CAS Number

137530-61-1

Smiles

C (C (N[C@H] (C (N[C@@H] ([C@@H] (C) C) C (O) =O) =O) CO) =O) (CC (NO) =O) CC (C) C

Molecular Formula

C16H29N3O7

Molecular Weight

375.42

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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