Banoxantrone (AQ4N)
Banoxantrone (AQ4N) is a hypoxia-activated prodrug that is reduced to its active form, AQ4, a potent topoisomerase II inhibitor. Its selective cytotoxicity in hypoxic cells, mediated through an iNOS-dependent mechanism, is enhanced by radiation, making it a valuable tool for studying tumor hypoxia and combination therapies in preclinical cancer research.
Product Specifications
CAS Number
136470-65-0
Field of Research
Immunology & Inflammation
Smiles
N (CCN (C) (C) =O) C1=C2C (=C (NCCN (C) (C) =O) C=C1) C (=O) C=3C (C2=O) =C (O) C=CC3O
Molecular Formula
C22H28N4O6
Molecular Weight
444.48
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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