ML309
ML309 is a potent and selective small molecule inhibitor of the R132H mutant IDH1 enzyme. It effectively suppresses 2-hydroxyglutarate (2-HG) production in U87 MG glioblastoma cells, making it a valuable research tool for studying mutant IDH1-driven cancers in both cellular and in vivo models.
Product Specifications
CAS Number
1355446-05-7
Smiles
C (N (C (CN1C=2C (N=C1) =CC=CC2) =O) C3=CC (F) =CC=C3) (C (NC4CCCC4) =O) C5=C (C) C=CC=C5
Molecular Formula
C29H29FN4O2
Molecular Weight
484.56
Storage Conditions
-20°C
Notes
For research use only.
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