6 (5H) -Phenanthridinone
6 (5H) -Phenanthridinone is a dual PARP1/PARP2 inhibitor that suppresses radiation-induced proliferation in murine lymphoma cells and reduces pro-inflammatory cytokine expression in lymphocytes. In vivo, it ameliorates EAE in rats by decreasing spinal cord iNOS and cytokine levels, while also reducing hepatic oxidative damage and serum LDH.
Product Specifications
CAS Number
1015-89-0
Field of Research
Epigenetics & Chromatin, Molecular Biology
Smiles
O=C1NC2=C (C=CC=C2) C2=C1C=CC=C2
Molecular Formula
C13H9NO
Molecular Weight
195.22
Storage Conditions
-20°C
Notes
For research use only.
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