PCSK9-IN-10
PCSK9-IN-10 is a potent, orally bioavailable small molecule inhibitor of PCSK9 (IC50 = 6.4 μM) . It functions by upregulating LDLR protein and downregulating PCSK9 expression, showing promise for in vitro and in vivo research in atherosclerosis and hyperlipidemia.
Product Specifications
CAS Number
368434-98-4
Product Name Alternative
PCSK9, PCSK9IN10, PCSK9-IN-10, Serine kinase, Ser/Thr Protease, threoninkinase, threonin kinase, Serinekinase
Field of Research
Cell Biology, Metabolism Research
Purity
98.85% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (13.39 mM) ; DMSO:225 mg/mL (602.55 mM)
Smiles
COCCNc1nc2n (C) c (=O) n (C) c (=O) c2n1Cc1cccc (OC) c1
Molecular Formula
C18H23N5O4
Molecular Weight
373.41
Storage Conditions
-20°C
Notes
For research use only.
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