CDK8-IN-13
CDK8-IN-13 is a potent, selective, and orally bioavailable CDK8 inhibitor (IC50 = 51.9 nM) . It induces apoptosis, suppresses p-STAT1 S727 and p-STAT5 S726, and demonstrates anti-tumor activity in research models, supporting its use in oncology and signal transduction studies.
Product Specifications
CAS Number
918523-75-8
Product Name Alternative
CDK8, CDK8IN13, CDK8-IN-13, Apoptosis
Field of Research
Cell Biology
Purity
99.19% (May vary between batches)
Solubility
DMSO:112.5 mg/mL (474.16 mM)
Smiles
C (N) (=O) C=1C=C (C=2C=C3C (=NC2) NC=C3) C=CC1
Molecular Formula
C14H11N3O
Molecular Weight
237.26
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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