PPK-188
PPK-188 (CFT) is a potent and selective covalent inhibitor of tryparedoxin (Tpx), a key enzyme in the trypanothione-based antioxidant defense of African trypanosomes. It demonstrates potent trypanocidal activity in vitro and has shown efficacy in reducing parasite burden in animal models of African trypanosomiasis, supporting its use in antiparasitic research.
Product Specifications
CAS Number
852400-39-6
Smiles
FC1=CC=C (C=C1) C1=CSC2=C1C (=O) N=C (CCl) N2
Molecular Formula
C13H8ClFN2OS
Molecular Weight
294.73
Storage Conditions
-20°C
Notes
For research use only.
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