IKKß-IN-124
IKKß-IN-124 is a selective allosteric inhibitor of IKKβ that stabilizes its inactive conformation, thereby preventing IκBα phosphorylation at Ser177/Ser181 and subsequent NF-κB activation. This compound is a valuable research tool for studying NF-κB signaling in cellular models of inflammation and oncology.
Product Specifications
CAS Number
825608-40-0
Smiles
CCOC1=C (C=CC (Cl) =C1Cl) S (=O) (=O) NC1CC (C) (C) NC (C) (C) C1
Molecular Formula
C17H26Cl2N2O3S
Molecular Weight
409.37
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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