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SC-10914

SC10914 is a potent and selective PARP1 inhibitor with low nanomolar IC50 values. It demonstrates strong anti-proliferative activity in BRCA1/2-deficient and PTEN-deficient cancer cell lines and exhibits significant in vivo anti-tumor efficacy in BRCA-mutant models. Its favorable pharmacokinetic profile supports its potential as a clinical candidate for targeted cancer therapy.

Product Specifications

CAS Number

76985-08-5

Smiles

NC (Cc1ccc (cc1) -c1ccccc1) C (O) =O

Molecular Formula

C15H15NO2

Molecular Weight

241.29

Storage Conditions

-20°C

Notes

For research use only.

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