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UCB-6786

UCB-6786 is a selective small molecule inhibitor of TNF signaling that functions by stabilizing an asymmetric conformation of the TNF trimer. This compound demonstrates a concentration-dependent inhibitory profile and is useful for investigating TNF-mediated pathways in both cellular and animal models of inflammation and autoimmunity.

Product Specifications

CAS Number

537018-21-6

Smiles

CC1=CC=CC=C1CN1C (CO) =NC2=CC=CC=C12

Molecular Formula

C16H16N2O

Molecular Weight

252.31

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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