RK-20448
RK-20448 is a cis-isomer of A-419259 and functions as a potent ATP-competitive inhibitor targeting Lck, Src, and VEGFR2/KDR, among other kinases like BLK and Fyn. This small molecule is a valuable research tool for studying T-cell signaling and angiogenesis in both cellular and biochemical assays.
Product Specifications
CAS Number
479501-40-1
Field of Research
Cardiovascular Research, Signal Transduction
Smiles
NC1=C2C (=CN (C2=NC=N1) [C@@H]3CC[C@@H] (CC3) N4CCN (C) CC4) C5=CC=C (OC6=CC=CC=C6) C=C5
Molecular Formula
C29H34N6O
Molecular Weight
482.62
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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