Lig4-4
Lig4-4 is a potent TREK-1 channel inhibitor (IC50 = 2.06 μM) with demonstrated neuroprotective properties in models of cerebral ischemia. Its mechanism involves modulating apoptosis-related proteins Bcl-2 and cleaved-caspase-3, making it a valuable research tool for studying ischemic injury and neuronal cell death in both in vitro and in vivo settings.
Product Specifications
CAS Number
3598-68-3
Field of Research
Epigenetics & Chromatin
Smiles
[O-][N+] (=O) CC1OC (=O) C2=CC=CC=C12
Molecular Formula
C9H7NO4
Molecular Weight
193.16
Storage Conditions
-20°C
Notes
For research use only.
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