[Gln144]-PLP (139-151)
[Gln144]-PLP (139-151) is an experimental antigen used to study T cells respond to both autoantigens and cross-reactive non-autoantigens. [Gln144]-PLP (139-151) activates T cells by binding to T-cell Receptor (TCR), which triggers an immune response. [Gln144]-PLP (139-151) can be used to study the regulation of autoimmune diseases[1].
Product Specifications
CAS Number
170033-42-8
Product Name Alternative
Q144-PLP (139-151)
UNSPSC
12352209
Target
Transmembrane Glycoprotein
Type
Peptides
Related Pathways
Immunology/Inflammation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/gln144-plp-139-151.html
Solubility
10 mM in DMSO
Smiles
O=C(N[C@@H](CO)C(N[C@@H](CC(C)C)C(NCC(N[C@@H](CCCCN)C(N[C@@H](CCC(N)=O)C(N[C@@H](CC(C)C)C(NCC(N[C@@H](CC1=CNC=N1)C(N2[C@@H](CCC2)C(N[C@@H](CC(O)=O)C(N[C@@H](CCCCN)C(N[C@@H](CC3=CC=CC=C3)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CC4=CNC=N4)N
Molecular Formula
C66H102N20O18
Molecular Weight
1463.64
References & Citations
[1]Munder M, et al. Reduced self-reactivity of an autoreactive T cell after activation with cross-reactive non–self-ligand[J]. The Journal of experimental medicine, 2002, 196 (9) : 1151-1162.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Frequently Asked Questions
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