Meclocycline
Meclocycline is a broad-spectrum tetracycline antibiotic that also exhibits cytoprotective properties in Huntington's disease research models. It reduces LDH release and cytotoxicity caused by mutant huntingtin (htt-N63-148Q) in PC12 cells without affecting protein levels, supporting its use in neuroprotection and cytotoxicity assays in vitro.
Product Specifications
CAS Number
2013-58-3
Field of Research
Infectious Disease & Virology, Pharmacology & Drug Discovery
Smiles
[H][C@@]12[C@@H] (O) [C@]3 ([H]) C (=C) c4c (Cl) ccc (O) c4C (=O) C3=C (O) [C@]1 (O) C (=O) C (C (N) =O) =C (O) [C@H]2N (C) C
Molecular Formula
C22H21ClN2O8
Molecular Weight
476.86
Storage Conditions
-20°C
Notes
For research use only.
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