NU1085
NU1085 is a potent PARP inhibitor (Ki = 6 nM) that enhances the cytotoxic effects of ionizing radiation and chemotherapeutic agents like temozolomide and topotecan. Its activity has been demonstrated in vitro across multiple human cancer cell lines, supporting research in DNA damage response and combination therapy for oncology.
Product Specifications
CAS Number
188106-83-4
Smiles
NC (=O) c1cccc2nc ([nH]c12) -c1ccc (O) cc1
Molecular Formula
C14H11N3O2
Molecular Weight
253.26
Storage Conditions
-20°C
Notes
For research use only.
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