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NU1085

NU1085 is a potent PARP inhibitor (Ki = 6 nM) that enhances the cytotoxic effects of ionizing radiation and chemotherapeutic agents like temozolomide and topotecan. Its activity has been demonstrated in vitro across multiple human cancer cell lines, supporting research in DNA damage response and combination therapy for oncology.

Product Specifications

CAS Number

188106-83-4

Smiles

NC (=O) c1cccc2nc ([nH]c12) -c1ccc (O) cc1

Molecular Formula

C14H11N3O2

Molecular Weight

253.26

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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