RKS-262
RKS262 is a cyclin/CDK inhibitor derived from Nifurtimox, which is in phase II trials for neuroblastoma. It shows potent in vitro cytotoxicity in NCI (60) assays, with high sensitivity in leukemia cells (GI50 ~10 nM) and resistance in some NSCLC lines (GI50 >1 μM) .
Product Specifications
CAS Number
1041469-97-9
Smiles
ClC=1C=2C (OC (=O) C1C=NN3C (C) CS (=O) (=O) CC3) =CC=C (Br) C2
Molecular Formula
C15H14BrClN2O4S
Molecular Weight
433.7
Storage Conditions
-20°C
Notes
For research use only.
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