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RKS-262

RKS262 is a cyclin/CDK inhibitor derived from Nifurtimox, which is in phase II trials for neuroblastoma. It shows potent in vitro cytotoxicity in NCI (60) assays, with high sensitivity in leukemia cells (GI50 ~10 nM) and resistance in some NSCLC lines (GI50 >1 μM) .

Product Specifications

CAS Number

1041469-97-9

Smiles

ClC=1C=2C (OC (=O) C1C=NN3C (C) CS (=O) (=O) CC3) =CC=C (Br) C2

Molecular Formula

C15H14BrClN2O4S

Molecular Weight

433.7

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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