SIM010603
SIM010603 is an orally bioavailable, multi-targeted tyrosine kinase inhibitor that potently inhibits KIT, VEGFR-2, PDGFR-β, RET, and FLT3. It blocks receptor phosphorylation and has demonstrated anti-angiogenic effects in cellular assays, including inhibition of endothelial cell proliferation and migration, supporting its research use in oncology and angiogenesis studies.
Product Specifications
CAS Number
1032265-67-0
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction
Smiles
O=C1/C (=C/2\C3=C (C (C (NCCN (C) C) =O) =C (C) N3) CCC2) /C=4C (N1) =CC=C (F) C4
Molecular Formula
C22H25FN4O2
Molecular Weight
396.46
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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