GSK1370319A
GSK1370319A is a potent and selective P2X7 receptor antagonist (IC50 = 3.2 nM) that blocks NLRP3 inflammasome assembly and IL-1β release in glial cells. It is a valuable research tool for studying neuroinflammation, demonstrating protective effects against neuronal loss in vitro and age-related synaptic deficits ex vivo.
Product Specifications
CAS Number
1001389-31-6
Smiles
C (NCC1=C (Cl) C=C (Cl) C=C1) (=O) [C@H]2N (C) C (=O) CC2
Molecular Formula
C13H14Cl2N2O2
Molecular Weight
301.17
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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