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EST64454 free base

EST64454 is a potent and selective σ1 receptor antagonist clinical candidate for pain treatment. Its favorable BCS Class I profile, characterized by high solubility and Caco-2 permeability, alongside high metabolic stability, supports its utility in both in vitro mechanistic studies and in vivo pain research models.

Product Specifications

CAS Number

1351438-26-0

Field of Research

Pharmacology & Drug Discovery

Smiles

C (OCCN1CCN (C (C) =O) CC1) C2=NN (C=C2) C3=CC (F) =C (F) C=C3

Molecular Formula

C18H22F2N4O2

Molecular Weight

364.39

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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