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Naldemedine tosylate

Naldemedine tosylate is a potent, orally active peripheral μ-opioid receptor antagonist (PAMORA) used to study opioid-induced constipation (OIC) . Research also indicates it may interact with the SARS-CoV-2 3CL protease, supporting investigations into its potential antiviral applications in vitro.

Product Specifications

CAS Number

1345728-04-2

Field of Research

Metabolism Research, Neuroscience, Pharmacology & Drug Discovery

Smiles

S (=O) (=O) (O) C1=CC=C (C) C=C1.O[C@]12[C@@]34C=5C (O[C@]3 (C (O) =C (C (NC (C) (C) C6=NC (=NO6) C7=CC=CC=C7) =O) C1) [H]) =C (O) C=CC5C[C@]2 (N (CC8CC8) CC4) [H]

Molecular Formula

C39H42N4O9S

Molecular Weight

742.84

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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