AM-8508
AM-8508 is a potent and selective PI3Kδ inhibitor with strong cellular and whole-blood activity (pAKT IC50 = 4.6 nM and 2.7 nM, respectively) . It demonstrates efficacy in vivo by inhibiting KLH-specific antibodies, supporting its research application in immunology and inflammatory disease models.
Product Specifications
CAS Number
1338483-67-2
Smiles
[C@H] (NC=1C (C#N) =C (N) N=CN1) (C) C=2N (C=3C (N2) =CC=C (F) C3) C=4C=CC=NC4
Molecular Formula
C19H15FN8
Molecular Weight
374.37
Storage Conditions
-20°C
Notes
For research use only.
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