MHY219
MHY219 is a potent novel HDAC inhibitor that induces apoptosis and cell cycle arrest in prostate cancer cells, notably upregulating androgen receptor expression. It demonstrates differential cytotoxicity across cell lines (DU145, LNCaP, PC3) and effectively increases histone H3 acetylation while downregulating class I HDACs. This compound is a valuable research tool for studying HDAC biology and cancer mechanisms in vitro.
Product Specifications
CAS Number
1326750-61-1
Smiles
N (C1=CC=C (NC (CCCCCCC (NO) =O) =O) C=C1) C2=CC=CC=C2
Molecular Formula
C20H25N3O3
Molecular Weight
355.43
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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