ICI-222155
ICI-222155 is a potent and selective small molecule inhibitor of aldose reductase (AKR1B1) . It is widely used in research to investigate the role of polyol pathway flux in diabetic complications, demonstrating efficacy in both in vitro enzymatic assays and in vivo animal models of neuropathy and cataract formation.
Product Specifications
CAS Number
132414-04-1
Smiles
S (CN (=O) =O) (=O) (=O) C1=C (C) C=C (N) C=C1C
Molecular Formula
C9H12N2O4S
Molecular Weight
244.27
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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