BAY-438
BAY-438 is a potent, orally bioavailable allosteric MEK inhibitor characterized by a prolonged half-life and minimal brain penetration. It demonstrates significant efficacy in K-Ras-mutated A549 cell line xenograft models, making it a valuable research tool for investigating targeted oncology therapies in both in vitro and in vivo settings.
Product Specifications
CAS Number
1295505-76-8
Smiles
N (C1=C (C (N) =O) C (OC2=CC (CNS (N) (=O) =O) =CC=C2) =CC (F) =C1F) C3=C (F) C=C (I) C=C3
Molecular Formula
C20H16F3IN4O4S
Molecular Weight
592.33
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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