Nanatinostat TFA
Nanatinostat (CHR-3996) is an oral, second-generation HDAC inhibitor with antineoplastic potential. It promotes histone hyperacetylation and gene expression changes leading to cell cycle arrest and apoptosis, showing enhanced effects on HSP70 and Bcl-2 compared to earlier inhibitors. It has been investigated in preclinical models for hematological and solid tumors.
Product Specifications
CAS Number
1256448-48-2
Field of Research
Cell Biology, Epigenetics & Chromatin, Immunology & Inflammation, Molecular Biology
Smiles
OC (=O) C (F) (F) F.[H][C@@]12CN (C[C@]1 ([H]) [C@H]2NCc1ccc2cc (F) ccc2n1) c1ncc (cn1) C (=O) NO
Molecular Formula
C22H20F4N6O4
Molecular Weight
508.43
Storage Conditions
-20°C
Notes
For research use only.
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