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Nanatinostat TFA

Nanatinostat (CHR-3996) is an oral, second-generation HDAC inhibitor with antineoplastic potential. It promotes histone hyperacetylation and gene expression changes leading to cell cycle arrest and apoptosis, showing enhanced effects on HSP70 and Bcl-2 compared to earlier inhibitors. It has been investigated in preclinical models for hematological and solid tumors.

Product Specifications

CAS Number

1256448-48-2

Field of Research

Cell Biology, Epigenetics & Chromatin, Immunology & Inflammation, Molecular Biology

Smiles

OC (=O) C (F) (F) F.[H][C@@]12CN (C[C@]1 ([H]) [C@H]2NCc1ccc2cc (F) ccc2n1) c1ncc (cn1) C (=O) NO

Molecular Formula

C22H20F4N6O4

Molecular Weight

508.43

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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