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Bisindolylmaleimide VIII

Bisindolylmaleimide VIII (Ro-31-7549) is a potent, selective PKC inhibitor effective against multiple isoforms. It suppresses T cell-mediated autoimmunity and potentiates Fas-induced apoptosis via PKC-independent mechanisms, making it a valuable tool for studying immune disorders and apoptosis in cellular and animal models.

Product Specifications

CAS Number

125313-65-7

Product Name Alternative

Apoptosis, Bis VIII, UNII-FC61260G4Q, Vortex, PKC, Ro-31-7549, Ro-31-7549 Monohydrate, Ro 31-7549, RO 318161

Field of Research

Cell Biology, Epigenetics & Chromatin, Signal Transduction

Purity

97.00% (May vary between batches)

Smiles

O=C1NC (=O) C (C2=CN (C=3C=CC=CC23) CCCN) =C1C4=CN (C=5C=CC=CC45) C

Molecular Formula

C24H22N4O2

Molecular Weight

398.46

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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