Bisindolylmaleimide VIII
Bisindolylmaleimide VIII (Ro-31-7549) is a potent, selective PKC inhibitor effective against multiple isoforms. It suppresses T cell-mediated autoimmunity and potentiates Fas-induced apoptosis via PKC-independent mechanisms, making it a valuable tool for studying immune disorders and apoptosis in cellular and animal models.
Product Specifications
CAS Number
125313-65-7
Product Name Alternative
Apoptosis, Bis VIII, UNII-FC61260G4Q, Vortex, PKC, Ro-31-7549, Ro-31-7549 Monohydrate, Ro 31-7549, RO 318161
Field of Research
Cell Biology, Epigenetics & Chromatin, Signal Transduction
Purity
97.00% (May vary between batches)
Smiles
O=C1NC (=O) C (C2=CN (C=3C=CC=CC23) CCCN) =C1C4=CN (C=5C=CC=CC45) C
Molecular Formula
C24H22N4O2
Molecular Weight
398.46
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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