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XMD-12

XMD-12 (Aurora-IN-1) is a potent, small-molecule inhibitor of Aurora kinases A, B, and C with IC50 values of 5.6, 18.4, and 24.6 nM, respectively. This compound is a valuable research tool for studying mitotic regulation and has been utilized in both cellular and in vivo models of cancer to investigate Aurora kinase function and therapeutic potential.

Product Specifications

CAS Number

1234481-08-3

Field of Research

Cell Biology, Epigenetics & Chromatin

Purity

99.94% (May vary between batches)

Smiles

O=C1C=2C=CC=CC2N (C3=NC (=NC=C3N1C) NC4=CC=C (C=C4) N5CCC (O) CC5) C

Molecular Formula

C24H26N6O2

Molecular Weight

430.5

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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