ARQ-736
ARQ 736 is a selective small-molecule BRAF inhibitor that potently targets cancer cells with BRAF mutations, which are prevalent in melanoma and linked to anti-EGFR therapy resistance in colon cancer. It is a valuable research tool for investigating the oncogenic MAPK pathway in both in vitro cellular assays and in vivo xenograft models.
Product Specifications
CAS Number
1228237-57-7
Field of Research
Signal Transduction
Smiles
[Na+].[Na+].Cn1ccc (n1) S (=O) (=O) N1CCC[C@H] (C1) Nc1nccc (n1) -c1c (nc2occn12) -c1cccc (OCOP ([O-]) ([O-]) =O) c1
Molecular Formula
C25H25N8Na2O8PS
Molecular Weight
674.54
Storage Conditions
-20°C
Notes
For research use only.
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