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JBIR-22

JBIR-22 is a small molecule that selectively inhibits the homodimerization of proteasome assembly factor 3 (PSMD3), disrupting proteasome biogenesis. This tool compound is valuable for in vitro studies investigating proteasome assembly mechanisms and cellular protein homeostasis, offering insights into potential therapeutic strategies targeting protein degradation pathways.

Product Specifications

CAS Number

1219095-76-7

Field of Research

Protein Biochemistry

Smiles

C (\O) (/[C@@H]1[C@@]2 ([C@@] (C=C[C@@H]1C) (CCCC2) [H]) [H]) =C/3\C (=O) [C@H] (C[C@] (C (C) C) (C (O) =O) O) N (C) C3=O

Molecular Formula

C23H33NO6

Molecular Weight

419.51

Storage Conditions

-20°C

Notes

For research use only.

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