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MPT0B214

MPT0B214 is a novel microtubule-targeting agent that binds the colchicine site, inhibiting tubulin polymerization and exerting potent cytotoxic effects across human cancer cell lines, including multidrug-resistant variants. It induces G2-M arrest, mitotic marker expression, and caspase-9-dependent apoptosis. This compound is a valuable research tool for investigating antimitotic mechanisms and overcoming drug resistance in oncology studies.

Product Specifications

CAS Number

1215208-65-3

Field of Research

Cell Biology, Metabolism Research, Protein Biochemistry, Signal Transduction

Smiles

NC=1C2=C (N=C (C (=O) C3=CC (OC) =C (OC) C (OC) =C3) C=C2) C=CC1OC

Molecular Formula

C20H20N2O5

Molecular Weight

368.38

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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