MPT0B214
MPT0B214 is a novel microtubule-targeting agent that binds the colchicine site, inhibiting tubulin polymerization and exerting potent cytotoxic effects across human cancer cell lines, including multidrug-resistant variants. It induces G2-M arrest, mitotic marker expression, and caspase-9-dependent apoptosis. This compound is a valuable research tool for investigating antimitotic mechanisms and overcoming drug resistance in oncology studies.
Product Specifications
CAS Number
1215208-65-3
Field of Research
Cell Biology, Metabolism Research, Protein Biochemistry, Signal Transduction
Smiles
NC=1C2=C (N=C (C (=O) C3=CC (OC) =C (OC) C (OC) =C3) C=C2) C=CC1OC
Molecular Formula
C20H20N2O5
Molecular Weight
368.38
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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