BPR1K653
BPR1K653 is a potent and selective Aurora-A/B kinase inhibitor with broad-spectrum anticancer activity in vitro, overcoming MDR1-mediated resistance. It induces endoreplication and apoptosis in cancer cells and demonstrates significant in vivo efficacy in xenograft models, including MDR1-positive tumors, supported by favorable pharmacokinetic profiles. This makes it a promising candidate for oncology research, particularly in studying drug-resistant malignancies.
Product Specifications
CAS Number
1192754-07-6
Smiles
Cl.CN (C) Cc1ccccc1NC (=O) Nc1ccc (CCNc2ncnc3oc (c (Cl) c23) -c2ccccc2) cc1
Molecular Formula
C30H29ClN6O2
Molecular Weight
541.04
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
LS010718-20ug 20 µg
NRG3 (NM_001165973) Human Over-expression Lysate
Sign In for Pricing
View Details 
MBS1167095-01 0.02 mg (E-Coli)
Recombinant Thermococcus onnurineus Translation initiation factor 2 subunit alpha (eIF2A)
Sign In for Pricing
View Details MBS1167095-02 0.02 mg (Yeast)
Recombinant Thermococcus onnurineus Translation initiation factor 2 subunit alpha (eIF2A)
Sign In for Pricing
View Details