CDKI-83
CDKI-83 is a potent and selective CDK9 inhibitor with anti-proliferative activity (GI50 <1 μM) in tumor cell lines. It induces apoptosis in A2780 ovarian cancer cells, evidenced by caspase-3 activation and sub-G1 accumulation, suggesting potential as an anticancer agent through combined CDK9/CDK1 inhibition.
Product Specifications
CAS Number
1189558-88-0
Field of Research
Cell Biology
Smiles
C (#N) C=1C (=NC (NC2=CC (S (=O) (=O) N3CCOCC3) =C (C) C=C2) =NC1) C=4SC (NC) =NC4C
Molecular Formula
C21H23N7O3S2
Molecular Weight
485.58
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS6121495-01 0.2 mL
EPHB4 (Ephrin type-B Receptor 4, Tyrosine-protein Kinase Receptor HTK, Tyrosine-protein Kinase TYRO11, HTK, TYRO11) (Azide free) (HRP)
Sign In for Pricing
View Details MBS6121495-02 5x 0.2 mL
EPHB4 (Ephrin type-B Receptor 4, Tyrosine-protein Kinase Receptor HTK, Tyrosine-protein Kinase TYRO11, HTK, TYRO11) (Azide free) (HRP)
Sign In for Pricing
View Details 
MBS6502884-02 5x 0.1 mL
Toll Like Receptor 2, NT (TLR2, CD282) (APC)
Sign In for Pricing
View Details