CDKI-83
CDKI-83 is a potent and selective CDK9 inhibitor with anti-proliferative activity (GI50 <1 μM) in tumor cell lines. It induces apoptosis in A2780 ovarian cancer cells, evidenced by caspase-3 activation and sub-G1 accumulation, suggesting potential as an anticancer agent through combined CDK9/CDK1 inhibition.
Product Specifications
CAS Number
1189558-88-0
Field of Research
Cell Biology
Smiles
C (#N) C=1C (=NC (NC2=CC (S (=O) (=O) N3CCOCC3) =C (C) C=C2) =NC1) C=4SC (NC) =NC4C
Molecular Formula
C21H23N7O3S2
Molecular Weight
485.58
Storage Conditions
-20°C
Notes
For research use only.
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