(±) 16 (17) -DiHDPA

(±) 16 (17) -DiHDPA is a epoxygenase metabolite of docosahexaenoic acid (HY-B2167) . (±) 16 (17) -DiHDPA inhibits platelet aggregation at concentrations below those affecting thromboxane synthesis[1][2].

Product Specifications

CAS Number

[1345275-27-5]

UNSPSC

12352211

Hazard Statement

H225, H319

Target

COX

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/racemic-16-17-dihdpa.html

Concentration

1.38 mM * 199.9 μL in Ethanol

Purity

99.0

Solubility

10 mM in DMSO

Smiles

CC/C=C\CC(O)C(O)C/C=C\C/C=C\C/C=C\C/C=C\CCC(O)=O

Molecular Formula

C22H34O4

Molecular Weight

362.50

Precautions

H225, H319

References & Citations

[1]VanRollins M, et al. Oxidation of docosahexaenoic acid by rat liver microsomes. J Biol Chem. 1984 May 10;259 (9) :5776-83.|[2]VanRollins M. Epoxygenase metabolites of docosahexaenoic and eicosapentaenoic acids inhibit platelet aggregation at concentrations below those affecting thromboxane synthesis. J Pharmacol Exp Ther. 1995 Aug;274 (2) :798-804.