Opaganib HCl
ABC294640 (Opaganib) is an orally bioavailable, selective sphingosine kinase-2 (SK2) inhibitor. By blocking SK2, it prevents the formation of pro-survival sphingosine-1-phosphate, inducing apoptosis and inhibiting proliferation in SK2-overexpressing cancer cells. It has demonstrated antitumor activity in preclinical in vitro and in vivo studies across various cancer models.
Product Specifications
CAS Number
1185157-59-8
Field of Research
Pharmacology & Drug Discovery
Smiles
C (NCC=1C=CN=CC1) (=O) C23CC4 (CC (C2) CC (C4) C3) C5=CC=C (Cl) C=C5.Cl
Molecular Formula
C23H26Cl2N2O
Molecular Weight
417.37
Storage Conditions
-20°C
Notes
For research use only.
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