6-Thio-GTP
6-Thio-GTP
Product Specifications
CAS Number
17670-19-8
Product Name Alternative
6-Thio-guanosine-5'-triphosphate, Sodium salt
Field of Research
Metabolism Research
Concentration
10 mM-11 mM
Purity
≥ 95% (HPLC)
Form
Solution in water; Color: colorless to slightly yellow; pH: 7.5 ± 0.5
Smiles
[C@@H]1 ([C@H] ([C@@H] (O[C@@H]1COP (=O) (OP (=O) (OP (=O) (O) O) O) O) n1c2c (nc1) c (nc (n2) N) S) O) O
Molecular Formula
C10H16N5O13P3S
Molecular Weight
Theoretical MW: 539.24 g/mol (free acid) ; Detected MW: 538.97 g/mol (free acid)
Storage Conditions
Store at -20 °C. Short term exposure (up to 1 week cumulative) to ambient temperature possible
Notes
For research use only.
Applications Notes
Allosteric effect on E.coli CTP-synthase; Inhibition of Vac-1-Rac signalling; Immunosuppression by blockade of GTPase activation; Immunosuppressive drug (transplantation, inflammation) . Spectroscopic Propertie: λmax 257 nm, ε 8.8 L mmol-1 cm-1 (Tris-HCl, pH 7.5), λmax 342 nm, ε 24.8 L mmol-1 cm-1 (Tris-HCl pH 7.5) .
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