8-Oxo-dGTP
8-Hydroxy-dGTP
Product Specifications
CAS Number
139307-94-1
Product Name Alternative
8-Hydroxy-dGTP, 8-Oxo-2'-deoxyguanosine-5'-triphosphate, Sodium salt
Concentration
10 mM-11 mM
Purity
≥ 95% (HPLC)
Form
Solution in water; Color: colorless to slightly yellow; pH: 7.5 ± 0.5
Smiles
Nc1[nH]c (=O) c2c (n (c (=O) [nH]2) [C@@H]2O[C@H] (COP (=O) (O) OP (=O) (O) OP (=O) (O) O) [C@@H] (O) C2) n1
Molecular Formula
C10H16N5O14P3
Molecular Weight
Theoretical MW: 523.18 g/mol (free acid) ; Detected MW: 522.99 g/mol (free acid)
Storage Conditions
Store at -20 °C. Short term exposure (up to 1 week cumulative) to ambient temperature possible
Notes
For research use only.
Applications Notes
Influence on base excision repair; Influence on erroneous incorporation by DNA-polymerases; Hydrolysis to 8-oxo-dGMP by E.-coli MutT; Triggering cell senescence through formation of ROS. Spectroscopic Propertie: λmax 245 nm, ε 12.3 L mmol-1 cm-1 (Tris-HCl, pH 7.5) .
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